Treatment of Anticoagulation

Question: Write an essay on Pharmacology? Answer: Joe Estaphalou was prescribed with sucralfate and warfarin. These two drugs have been used for the treatment of anticoagulation. But when these two drugs are taken together, it will affect each others function. If sucralfate is taken orally then it has an adverse effect on the warfarin (Siest, 2015). As sucralfate suppress the absorption of warfarin by the stomach and intestine. As a result the level of warfarin becomes reduced in the blood if they are taken together. On the other hand warfarin has the same effect on the absorption of the sucralfate if taken by mouth. The interaction of these two medicine categorized in the minor. Core drug knowledge includes the knowledge of pharmacotherapeutics, pharmacokinetics, pharmacodynamics, contraindications and precautions of the drugs to be used, adverse effects of every drug, and also the knowledge of the drug interaction. Core drug knowledge also includes the knowledge about the drugs that can be taken orally(Aschenbrenner and Venable, 2009). The knowledge provides the knowledge that not all drugs can be taken orally. Along with this it provides the fact that food can interfere the absorption of the drug and it also has the effect on the dissolution of the drugs. The laboratory values include the laboratory test result of the human body system like red blood cell count, platelet count, white blood cell count etc. The core knowledge of the drug can affect the laboratory values as the core knowledge of drug can affect the laboratory values. The variables that can be considered as the most important variable are the health status of the patient, life span of the patient, gender, lifestyle lead by the patient, diet and habits, environment, cultural and inherited traits etc. The considerable variable of the health status includes the information about the health related issues while the patient receiving the drug therapy, the information about the current issues related t the health of the patient (Siest, 2015). The life span is an important factor or variable to be considered when administering the drug to the patient if there is a consideration of the developing fetus. There are some aspects present in the core drug knowledge that to be considered in the interaction with the core patient variables. They are as follows, the information of the patient current health status that is, the occurrence of any kind of impairment in the organ functioning, the blood pressure of the patient, if the vital signs are all ok and normal, the heart rate , the diet of the patient and the life style lead by the patient(Aschenbrenner and Venable, 2009). The nursing assessment includes six steps; they are diagnosis of the disease, identification of the result, planning for the future therapy, intervention and at last evaluation. Nursing assessments that are important for the drug therapy are as follows, the health status of the patient, that the patient has any kind of disease, illness, organ dysfunction, chronic condition etc. after that the considerable factor is the age, reproductive stage, psychologic development and gender. Nurses along with this need to know what kind of drug the patient has used and prescribed for. Nursing assessment also includes the collecting the information of the community background of the patient that can affect the therapy procedure of the patient (Siest, 2015). The assessments that can tell the possible adverse effect of the drug therapy are as follows; if the patient has any kind of allergy from any drug, All the laboratory findings have to be observed as evidence; otherwise the drug therapy may affect the health of the patient. Finding of the drugs that are to be administered intravenously or orally to the patient. Monitoring the blood pressure before administering of any drug. To maximize the therapeutic effect of any drug the nurse must know the desired out come of the drug used for the patient. The nurse should administer the drug in a manner that can be absorbed by the patients system. The nurse should know the appropriate time of the administration of the drug to the patient(Aschenbrenner and Venable, 2009). Nurse should maintain the laboratory values at the time o administration of the drug t the patient. To minimize the adverse effect of the drug nurse should follow some rule at the time of applying the drug to the patient. The nurse should verify the patient to not having any kind of allergy. The drug should be administered maintaining a standard safety protocol. The nurse should have the laboratory report of the patient; therefore she can plan the drug therapy in accordance with the report. Nurse should discontinue the drug therapy if there is any kind of complications take place (Siest, 2015). Nurse should report the doctor if any kind of adverse effect if she found any kind of complication. Before administering of any drug blood pressure of the patient should be checked by the nurse. Mr. Estaphalou required the education for his drug therapy are like the name of the drug including both generic name and trade name, the function of the drug, is there s any kind of contradiction after taking the drug. Nurse should include the timing of taking the drug, the procedure of taking the drug, what to do if the dose is forgotten by the patient, during the drug taking period what kind of activities the patient should avoid. The guidelines should include the information about the interaction between the drug and the food, any kind of interaction of drug to drug if present should be mentioned in the guideline. If there is any recommendation for the storage of the drug then it should be mentioned there(Aschenbrenner and Venable, 2009). Reference List Aschenbrenner, D. and Venable, S. (2009).Drug therapy in nursing. Philadelphia: Wolters Kluwer Health/Lippincott Williams Wilkins. Siest, G. (2015). From DMDI Drug Metabolism and Drug Interactions to DMPT Drug Metabolism and Personalized Therapy.Drug Metabolism and Personalized Therapy, 30(1), p.1.